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Professor Carreira's research program focuses on the asymmetric synthesis of biologically active, stereochemically complex, natural products. Target molecules are selected which pose unique challenges in asymmetric bond construction. A complex multistep synthesis endeavor provides a goal-oriented setting within which to engage in reaction innovation and design. Drawing from the areas of organometallic chemistry, coordination chemistry, and molecular recognition, Carreira's group is developing catalytic and stoichiometric reagents for asymmetric stereocontrol.

Carreira Group Ticino 2019
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凯时官网地址安卓下载

Check out these recent publications from the Carreira lab:

M. Brandstätter, N. Huwyler, E.M. Carreira, Chem. Sci.凯时官网地址地址代理, Advanced Article. Gold(I)-catalyzed stereoselective cyclization of 1,3-enyne aldehydes by a 1,3-acyloxy migration/Nazarov cyclization/aldol addition cascade.凯时官网地址二维码首页

T. Sandmeier, F.W. Goetzke, S. Krautwald, E.M. Carreira, J. Am. Chem. Soc.凯时官网地址地址代理, 141凯时官网地址娱乐 Iridium-Catalyzed Enantioselective Allylic Substitution with Aqueous Solutions of Nucleophiles.凯时官网地址娱乐

凯时官网地址地址代理凯时官网地址官网appS.L. Rössler, D.A. Petrone, E.M. Carreira, Acc. Chem. Res.凯时官网地址地址代理, asap. Iridium-Catalyzed Asymmetric Synthesis of Functionally Rich Molecules Enabled by (Phosphoramidite,Olefin) Ligands.凯时官网地址注册检测

P. Sondermann, E.M. Carreira, J. Am. Chem. Soc.,凯时官网地址官网app, 141凯时官网地址代理在线 Stereochemical Revision, Total Synthesis, and Solution State Conformation of the Complex Chlorosulfolipid Mytilipin B.凯时官网地址在线二维码

Y. Sempere, J.L. Alfke, S.L. Rössler, E.M. Carreira, Angew. Chem. Int. Ed.,凯时官网地址娱乐, 58凯时官网地址注册检测Morpholine Ketene Aminal as Amide Enolate Surrogate in Iridium‐Catalyzed Asymmetric Allylic Alkylation.凯时官网地址官网二维码

凯时官网地址二维码网址B.S. Schreib, E.M. Carreira, J. Am. Chem. Soc., 凯时官网地址检测首页, 141凯时官网地址注册地址. Palladium-Catalyzed Regioselective C−H Iodination of Unactivated Alkenes.凯时官网地址地址代理

M. Isomura, D.A. Petrone, E.M. Carreira, J. Am. Chem. Soc., 凯时官网地址地址注册, 141, 4738–4748. Coordination-Induced Stereocontrol over Carbocations: Asymmetric Reductive Deoxygenation of Racemic Tertiary Alcohols.凯时官网地址在线

M. Brandstätter, M. Freis, N. Huwyler, E.M. Carreira, Angew. Chem. Int. Ed., 凯时官网地址在线二维码, 58, 2490–2494Total Synthesis of (–)‐Merochlorin A.凯时官网地址检测首页

S.L. Rössler, B.J. Jelier, P.F. Tripet, A. Shemet, G. Jeschke, A. Togni, E.M. Carreira, Angew. Chem. Int. Ed. 凯时官网地址安卓手机, 131, 536 –541. Pyridyl Radical Cation for C–H Amination of Arenes凯时官网地址注册地址.

J. Boshkow, T. Scattolin, F. Schoenebeck, E.M. Carreira, Helv. Chim. Acta 凯时官网地址官网app, 101, e18001. [1,3]‐Sigmatropic Shift of an Allylic Chloride.凯时官网地址地址代理

M.J.R. Richter, M. Schneider, M. Brandstätter, S. Krautwald, E.M. Carreira, J. Am. Chem. Soc., 凯时官网地址官网二维码, 140, 16704–16710. Total Synthesis of (–)-Mitrephorone A.凯时官网地址代理在线

A. Chicca, M.A. Schafroth, I. Reynoso-Moreno, R. Erni, V. Petrucci, E.M. Carreira, J. Gertsch, Sci. Adv. 凯时官网地址官网地址, 4, 1–10. Uncovering the psychoactivity of a cannabinoid from liverworts associated with a legal high.凯时官网地址安卓下载

J.F. Teiber, J. Xiao, G.L. Kramer, S. Ogawa, C. Ebner, H. Wolleb, E.M. Carreira, D.M. Shih, R.W. Haley, Biochem. Biophys. Res. 凯时官网地址注册检测, 505, 87–92. Identification of biologically active δ-lactone eicosanoids as paraoxonase substrates.凯时官网地址安卓下载

A.G. Kravina, E.M. Carreira, Angew. Chem. Int. Ed. 凯时官网地址地址注册, 57, 13159–13162. Total Synthesis of Epicolactone.凯时官网地址地址代理

N.Hauser, P. Kraft, E.M. Carreira, Synthesis 凯时官网地址在线, 50,4490–4500. Unconventional Rose Odorants: Serendipitous Discovery and Unique Olfactory Properties of 2,2-Bis(prenyl)-3-oxobutyronitrile and Its Derivatives.凯时官网地址二维码首页

Y. Sempere, E.M. Carreira, Angew. Chem. Int. Ed., 凯时官网地址官网二维码, 57, 7654–7658. Trimethyl Orthoacetate and Ethylene Glycol Mono-Vinyl Ether as Enolate Surrogates in Enantioselective Iridium-Catalyzed Allylation.凯时官网地址地址代理

H. Wolleb, S. Ogawa, M. Schneider, A. Shemet, J. Muri, M. Kopf, E.M. Carreira, Org. Lett., 凯时官网地址娱乐20, 3014−3016. Synthesis and Structure–Activity Relationship Studies of Anti-Inflammatory Epoxyisoprostane Analogues.凯时官网地址二维码网址

N. Sobotzki, M.A. Schafroth, A. Rudnicka, A. Koetemann, F. Marty, S. Goetze, Y. Yamauchi, E.M. Carreira, B. Wollscheid, Nat. Comm. 凯时官网地址官网app, 9, 1519. HATRIC-based identification of receptors for orphan ligands.凯时官网地址官网二维码

N. Sievertsen, E.M. Carreira, Chimia 凯时官网地址安卓下载, 72, 44–47. Apoc Social: A Mobile Interactive and Social Learning Platform for Collaborative Solving of Advanced Problems in Organic Chemistry凯时官网地址官网app.

D.A. Petrone, M. Isomura, I. Franzoni, S.L. Rössler, E.M. Carreira, J. Am. Chem. Soc. 凯时官网地址地址代理, 140, 4697–4704. Allenylic Carbonates in Enantioselective Iridium-Catalyzed Alkylations.凯时官网地址网址

E.M. Carreira, J. Isr. Chem. 凯时官网地址二维码网址, 59, 114–121. Natural Products Synthesis: A Personal Retrospective and Outlook.凯时官网地址下载下载

M. Soethoudt, S.C. Stolze, M.V. Westphal, L. van Stralen, A. Martella, E.J. van Rooden, W. Guba, Z.V. Varga, H. Deng, S.I. van Kasteren, U. Grether, A.P. IJzerman, P. Pacher, E.M. Carreira, H.S. Overkleeft, A. Ioan-Facsinay, L.H. Heitman, M. van der Stelt, J. Am. Chem. Soc. 凯时官网地址安卓下载, 140, 6067–6075. Selective Photoaffinity Probe That Enables Assessment of Cannabinoid CB2 Receptor Expression and Ligand Engagement in Human Cells.凯时官网地址二维码网址

L.J. Nannini, Suren J.Nemat, E.M. Carreira, Angew. Chem. Int. Ed., 凯时官网地址安卓下载, 130, 831–834. Total Synthesis of (+)-Sarcophytin凯时官网地址网站ios.

M.V. Westphal, M.A. Schafroth, R.C. Sarott, M.A. Imhof, C.P. Bold, P. Leippe, A. Dhopeshwarkar, J.M. Grandner, V. Katritch, K. Mackie, D. Trauner, E.M. Carreira, J.A. Frank, J. Am. Chem. Soc. 凯时官网地址安卓下载, 139, 18206–18212. Synthesis of Photoswitchable Δ9-Tetrahydrocannabinol Derivatives Enables Optical Control of Cannabinoid Receptor 1 Signaling.凯时官网地址地址代理

 

 
 
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